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Also when for the second dose small-size PEGylated liposomes were used, the ABC phenomenon was observed after induction by a first injection of PL, whereas plasma kinetics and organ uptake of a second dose of negatively charged CL (NCL, 110 nm) or small-sized NCL (SNCL, 60 nm) were not altered.
A first injection has failed to clear up the problem, so the 37-year-old will have a second course of treatment.
Mice received a first injection of MDMA and the locomotor activity was recorded for two hours (two-injection protocol).
Further, we find in vivo that a first injection of each agonist in DOR-eGFP mice reduces inflammatory pain, with similar efficacy for the two drugs.
This is of particular importance when considering the fact that the immune response against AAV vectors after a first injection hinders future re-administrations.
A first injection of a 10 µM H2O2 solution initiated its reduction by the CAT contained in the diluted sample, which was added to a 100 µl phosphate buffer 100 mM (pH 7.8) containing 0.6 mM EDTA.
Similar(45)
The mRNA is designed so that the morpholino binding site is absent and is coinjected with the morpholino or injected separately in a second injection.
A second injection of radiopharmaceutical (10 MBq/kg) was injected ≥10.1 min after the first injection, at the end of the second minute of adenosine intravenous infusion.
For BrdU cumulative labelling experiments, BrdU was injected intraperitoneally in P4 pups, followed by a second injection at P5 (24 hours later).
A control group of rats were injected with endotoxin-free saline, and they received a second injection of saline on day 21 (SAL + SAL).
The patient became ill soon after receiving a second injection, the drug agency said.
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