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This PubChem3D similarity search is a multistep process designed: to filter out conformer pairs that cannot possibly be neighbors, to generate a near-optimal superposition between conformer pairs, and to perform a final optimization of the superposition to maximize the shape volume overlap between conformer pairs.
A final optimization of the significant factors was carried out using a Doehlert matrix.
A final optimization of the micro-PEG assay established that amounts as low as 0.1-0.2 0.1-0.2be used.
In order to determine the best conditions for preconcentration and determination of copper, a final optimization of the significant factors was carried out using a central composite design (CCD).
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A final optimization step using the complete data set yielded PSAMs for 20 of 45 RBPs (see Table S1 and Table S5).
RSM is one of the widely used statistical approaches for final optimization of process parameters which plays an important role in designing experiments (DOE).
Final optimization of formula was performed by response surface methodology using a central composite design.
With a spreadsheet package and a computer aided design (CAD) tool, the product model generation, change management and final optimization of the case assembly including its bulk shape, have been achieved.
Comparison of the green and blue lines illustrates the improvement of transmission achieved by final optimization of the corrugation on the exit face of the Al layer.
After the final optimization of the medium another bioreactor cultivation of B. subtilis DSM 10T with integrated foam fractionation was conducted to compare production rates of Surfactin with results obtained from cultivations presented in Willenbacher et al. (2014).
Another of the novelties of the proposed algorithm is the incorporation of local search algorithms in three stages of the algorithm: initialization of the population, evolution of the individuals and final optimization of the Pareto front.
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CEO of Professional Science Editing for Scientists @ prosciediting.com