In the final instance of Tay Sachs disease, the neuraminidase genes sit on a metabolic bypass pathway which may moderate the clinical severity (29) although recent work has called this interpretation into question (30).
The big "get" is Icecrown Citadel, the final instance of Wrath of the Lich King.
As one of the only areas of ideological overlap between Obama and the GOP-controlled Congress, trade may prove to be the final instance of substantive legislating in the Obama era.
Andrelton Simmons and Cozart, however, were unable to deliver the hit that could have tied the score, setting up the Angels for one final instance of coming up short.
The initial indignation, however, did not last; in hindsight, it seems one of the final instances of a broad cultural unity that now seems lost to this country forever.
In the final instance, codon harmonization of the full gene sequence of MSP142 yielded the highest level of soluble protein compared with both the single-pause-site mutant and the 5′-end harmonized variants (Fig. 1, lane 3, and Fig. 2D) [ 62, 63].
The final instance was Joan of Arc, the troubled epic he hoped would surpass Gone With the Wind but which brought about his death in 1949.
There is no Supreme Court of final instance.
However, it also has to be noted that what stops all of these idealist thinkers and poets from, in the final instance, being "religious", is their recognition of the not-yetness of the trends and tendencies latent within the human spirit.
It is power which in the final instance is necessary for the enforcement of conflicting views of what I ought to do; I can only choose not to obey if I possess the power to resist the demands of the state or if I am willing to accept the consequences of the state's superiority of coercive force.
We are all implicated and we must all act, deliberately and with urgency - because inclusive capitalism is, in the final instance, the only defensible form of capitalism.
