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Justyna Jupowicz-Kozak quote

Justyna Jupowicz-Kozak

CEO of Professional Science Editing for Scientists @ prosciediting.com

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a final alignment

Grammar usage guide and real-world examples

USAGE SUMMARY

The phrase 'a final alignment' is correct and can be used in written English.
You can use it when referring to a situation or process of coming to an agreement or understanding, especially after a period of disagreement and uncertainty. For example: After much discussion and debate, the two parties finally reached a final alignment on the terms of the agreement.

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

42 human-written examples

Application of Gblocks [ 65] at default settings lead to a final alignment of 2572 reliably aligned amino acids.

Sequences of CYTB and IRBP were edited and aligned in SeqScape v2.5 (Applied Biosystems), producing a final alignment of 1140 and 1276 bp, respectively.

A final alignment was created in which the POMGnT1 sequence was aligned with the sequence of the homology model.

Finally the 13 data set were concatenated, species-by-species, to produce a final alignment of 105 sequences, 12552 nucleotide and 4184 amino acid positions (alignments available upon request).

Submatrix matches are then reassembled into a final alignment via a standard score-maximization algorithm — the original version of DALI used a Monte Carlo simulation to maximize a structural similarity score that is a function of the distances between putative corresponding atoms.

As discussed in Observation 1, a final alignment is generated by extending a seed from its end positions.

Science

Plosone
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Human-verified similar examples from authoritative sources

Similar Expressions

18 human-written examples

However, the spread on the top left corner of the plot means that even when the MSA corresponds only to a small portion of the final alignment, a high score could be obtained.

Science

Plosone

Being much more recent than the receptors containing a CEGCKG or similar motif, the very high similarity for the DNA binding domains of 3-ketosteroid receptors means that, in order to produce a well sampled final alignment, the procedures described in Materials and methods remove most of those receptors from the DBD alignment, resulting in only five sequences with a CGSCKV motif.

After cleaning the raw data from ambiguously aligned positions, the final alignment had a length of 11,276 amino acids.

Sequences of COI (263 bp) and COII (341 bp) fragments were then concatenated, resulting in a 604 bp-long final alignment.

Before the final alignment, a Pfam v27.0 domain search (Punta et al. 2012) was performed and all sequences were trimmed manually at ±20 amino acids up- and downstream from the predicted seven-transmembrane domain (7tm_1; PF00001).

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Expert writing Tips

Best practice

When using "a final alignment", ensure that the context clearly indicates what is being aligned, whether it's data, sequences, or strategic goals.

Common error

Avoid assuming the alignment's scope is universally understood; explicitly state what is aligned and its purpose to prevent ambiguity.

Antonio Rotolo, PhD - Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Antonio Rotolo, PhD

Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Source & Trust

82%

Authority and reliability

4.5/5

Expert rating

Real-world application tested

Linguistic Context

The phrase "a final alignment" functions primarily as a noun phrase, often serving as the subject or object of a sentence. As Ludwig AI exemplifies, it signifies the completed state of a process involving arrangement or agreement.

Expression frequency: Common

Frequent in

Science

89%

Wiki

3%

Formal & Business

3%

Less common in

News & Media

2%

Encyclopedias

1%

Reference

1%

Ludwig's WRAP-UP

In summary, "a final alignment" is a grammatically correct and commonly used noun phrase, primarily within scientific and technical contexts. As Ludwig AI confirms, it signifies the end result of a process, such as arranging data or reaching an agreement. Its usage is most frequent in scientific publications and academic research, indicating a formal register. When using this phrase, ensure that the context clearly specifies what is being aligned to avoid ambiguity. Alternatives like "definitive arrangement" or "conclusive agreement" can be considered based on the specific nuance you wish to convey.

FAQs

How is "a final alignment" typically used in scientific research?

In scientific research, "a final alignment" often refers to the end result of aligning biological sequences (DNA, RNA, or protein) for comparative analysis, phylogenetic studies, or identifying conserved regions. It represents the optimized arrangement of sequences after gap adjustments and error corrections.

What does it mean to reach "a final alignment" in a business context?

In a business setting, reaching "a final alignment" suggests that all departments or stakeholders have come to an agreement on strategies, goals, or project plans, thus providing clarity on directions and next steps.

What are some alternatives to using the phrase "a final alignment"?

Depending on the context, you could use phrases like "definitive arrangement", "conclusive agreement", or "ultimate consensus" to convey a similar meaning.

How does "a final alignment" differ from an initial alignment?

An initial alignment is a preliminary arrangement of data or strategies, often containing errors or gaps. "A final alignment", on the other hand, is a refined version that has been optimized for accuracy and consistency, representing the agreed-upon standard.

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Authority and reliability

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Real-world application tested

Most frequent sentences: