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With respect to intercellular distribution, heterogeneity was a feature of staining commonly observed within invasive cancers, with some cases containing intensely stained regions immediately adjacent to negative regions.
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Interestingly this initial investigation suggested that immunopositive staining is more a feature of squamous cell carcinoma (8/11 with a score of 2 or 3, average score = 1.91) than adenocarcinoma (5 samples, none with score 3, average score = 1.8).
Traditionally, this group is considered to include Gram-positive bacteria with a low GC content in their DNA, although recent studies have shown that Gram-positive staining is not a feature of many Firmicutes.
Two prominent features of staining were evident: immunolabeling of degenerating astrocytes in proximity to blood vessels and staining within plaque-rich regions of the AD brain.
The variable 'goodness-of-fit' is a very robust texture analysis feature, since it is much more independent of staining variations than the FD [111].
The association of staining patterns with clinicopathological features was assessed with the χ2 test and the unpaired Student t-test.
Figure 2A shows the representative features of APC7 staining scores of 0 to 3+, and Fig. 2B shows the immunoblotting results for three representative tissues with different intensity scores.
To analyze actin polymerization as a typical feature of cell motility, we stained cells for filamentous actin (F-actin).
To test whether binding to late apoptotic cells is a specific feature of vitronectin, we performed staining of late apoptotic cells with antibodies to human vitronectin and human albumin.
Furthermore, VGAT and VGLUT2 staining both show a punctuate staining pattern; a common feature of presynaptic proteins.
While the physics engine allows for spectacular rendering of destruction of the game environment, which is a main feature of the game, Coffee Stain acknowledged the downside of this as "it would synchronise terribly in multiplayer".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com