Sentence examples for a feature of a compound from inspiring English sources
Additionally, the weight w ij = α i y i x ij of a feature of a compound with α i > 0 is positive if the class of a compound x i is labeled active (y i = +1) and negative otherwise.
If a user wants to obtain the value of a ChEBI feature of a compound, it is necessary to use a property connecting the compound with the resource representing the ChEBI feature, and then to use the property connecting this resource with the feature value.
The feature maps permit to compute similarity matrices with jCompoundMapper on the full set of features of a compound C, without introducing noise by hashing.
The goal of this work was to introduce a new binary fingerprint that encodes the main features of a compound data set.
In all implementations the features of a compound C are distinguishable by recurrence, which means that we include a feature if the id of a feature is different from the previously extracted features.
Each ECFP feature of a fingerprinted compound represents a circular substructure around a center atom.
A common feature of active compounds is an ortho-hydroxy group in the phenyl ring.
In the case of MeHg, triggering of cytotoxic responses is rather a specific feature of the compound (protein modifier, trigger of oxidative stress).
A characteristic feature of SINE compound treatment on cells both in vitro and in vivo is the nuclear retention of key XPO1 cargoes [reviewed in [ 54]].
Furthermore, in a recent small-molecule screen, Isojima and colleagues found that a common feature of compounds causing an increase in circadian period was inhibition of CK1δ/CK1ε activity, and RNA interference targeting either kinase lengthened period in human U2 osteosarcoma cells, although reducing expression of CK1δ by RNA interference had a larger effect than knocking down CK1ε [25].
