This is in line with the fact that hypothalamic AgRP content and AgRP to POMC increased ratio is a key feature associated to the hypophagic response to protein feeding in the normal situation (results of Fig. 2).
In our study, nest boxes were cleaned after each breeding period, so visual signals of the presence of old nests or ectoparasites could not be utilized directly by the individuals – instead, avoidance mechanism was indirect, via responding to a nest-site feature associated to con- or heterospecifics.
A genomic variant that leads to a substitution in a particular residue of a protein isoform is linked to features associated to that amino acid.
A design space normally divides the features associated to each artifact into two groups functional properties and structural features.
Among these four genera, Creagrutus (71 species) is the only one supported as a monophyletic group based on apomorphic features associated to jaws and teeth [ 16].
Interestingly, several PPIs (omeprazole, ESOM and pantoprazole) raise lysosomal pH and decrease intracellular pH, a feature associated with their ability to sensitize cancer cells to chemotherapeutics as well.
Furthermore HCC1428-LTED lost expression of both CXCL11 and CXCL12, a feature associated with chemotactic response to ligand gradients and not associated with proliferation [ 30].
Given the link to BRCA1 defects, we hypothesize that this phenotype i.e., RB/p16 dysfunctional TNBCs could be promoted by DNA repair defects, a feature associated with enhanced sensitivity to DNA damaging agents often used in treatment of hormone-receptor negative disease.
Conclusion Pharmacological MMP-13 inhibition yields collagen accumulation in plaques (a feature associated in humans with resistance to rupture), even in established plaques.
The interruption of late replicating L1-rich AT isohores by small early replicating (EtoL) domains and early replicating L1-poor GC isohores by late replicating (LtoE) domains was also thought to be a feature associated with pluripotency [ 45].
