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For a hybridization event to be a favourable explanation when groups exchange positions between two trees, the age of the split disagreeing with the species tree should be younger than in the species tree [ 23].
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This may be a more favourable explanation as the mutations are shared by only two elements, although these sequences could suggest a source gene active at very low levels.
Resulting from an increased cell proliferation at colonic crypts bordering the anastomotic line [ 4], an increased cellular activity near the anastomosis [ 23], and from a chronic inflammatory effect by suture [ 5- 9, 33], the hypothesis of a higher susceptibility of the anastomotic mucosa represents the most favourable explanation for these recurrences.
These authors also note the lower levels of young Alu insertions in the chimpanzee relative to the human genome, and suggest a general increase in retrotranspositional activity in humans as the most favourable explanation.
But it is still a more rewarding start point than any number of more favourable explanations.
One possible pathogenic explanation to a favourable effect of treatment with corticosteroids would be a stabilization of such plaques.
The results indicated that, to some extent, domains of positive communication (i.e. reassurance, a clear explanation and a favourable prognosis) were associated with preferable patient outcomes.
The provision of reassurance appeared to contribute to patients feeling better; a clear explanation and a favourable prognosis appeared to alleviate patients' functional health status as well.
The observation protocol included the validated Active Listening Observation Scale (ALOS-global), as well as three domains of positive communication, i.e. providing reassurance, a clear explanation, and a favourable prognosis.
My argument is that molecular descriptions and explanations have been pushed so far that they have reached their limits: these limits constitute a favourable niche in which physical explanations can develop.
One explanation is that the vicinity of plasma and endosomal membranes is a favourable niche for calpain activation; in vitro experiments have shown that phospholipids, a major component of plasma membranes, lower the Ca2+ concentration required to activate calpain.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com