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A fast release of the unmodified drug (85 ± 10% of 9-AC in 12 h) was detected in rat cecal contents.
The film-coating showed the capability to breach after a lag time, immediately providing a fast release of the drug during the disintegration of the core.
Microspheres fabricated at a low volume ratio of oil phase to internal water phase and a low polymer concentration tend to have a large surface area, a low bulk density, resulting in a high initial burst and a fast release of BSA.
It is inferred that a higher yield is obtained with an increase of temperature in the forced mode of operation as compared to that in the natural mode of operation due to a fast release of heat from the condensing cover.
All NPs exhibited a fast release of Sal at the initial stage and a sustained release in the following time.
When smoking marijuana is the principal method of consumption, there is a fast release of THC via inhalation into the general circulation (Huestis [2007]).
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Furthermore, FXa-cleavable gels enabled a faster release of heparin, which was attributed to the lower affinity of the factor for heparin.
Results clearly show that the alkane oil has a plasticizing effect on the PMMA shell, thereby generating a faster release of 4-nitroanisole.
Comparative evaluation of the in vitro release of diclofenac sodium from the matrix tablets of gum kondagogu and gum kondagogu-g-poly acrylamide) revealed a faster release of drug from gum kondagogu-g-poly acrylamide).
The hybrid scaffolds bearing Schiff base linkage between the polymer and siloxane, unlike the stable linkages in earlier reports, are expected to give a faster release of siloxanes and enhancement in osteogenesis.
The focus of present investigation was to assess the utility of non-destructive techniques in the evaluation of risperidone solid dispersions (SD) with methyl-β-cyclodextrin (MBCD) and subsequent incorporation of the SD into orally disintegrating tablets (ODT) for a faster release of risperidone.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com