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The phrase "a failure to modify" is correct and usable in written English.
It can be used in contexts where you are discussing the lack of changes or adjustments made to something, such as a plan, document, or behavior.
Example: "The project's delay was largely due to a failure to modify the original timeline based on the new requirements."
Alternatives: "an inability to adjust" or "a neglect to change".
Exact(2)
Such a failure to modify the TCR repertoire of self-reactive cells can be the result of two mechanisms.
We suspect that this may be due to either a failure to modify PCNA within a trimer already bearing one or two ubiquitin moieties, or simply due to the low concentration of unmodified PCNA in the reaction.
Similar(58)
The progress report also provided a breakdown by state and subject of some 1,400 complaints already received by the monitor through a Web site, primarily about faulty modifications or failure to modify, or about the banks' customer service.
Taylor and other consumer advocates have said the problem spans from the loan origination that inflated the housing bubble to the failure to modify mortgages after it burst, not simply when a foreclosure is already inevitable.
He added that Congress's failure to modify the law after more recent decisions imposing that heightened standard was evidence that it had "actively acquiesced" in the interpretation.
The failure to reengage in negotiations before September or the failure to modify any resolution passed by the UN to produce positive momentum would usher in a period of instability with unpredictable consequences for all: the United States, Israel and the Palestinians.
In contrast, other studies found that the most common reasons for inappropriate inpatient prescriptions for vancomycin were surgical prophylaxis and failure to modify prescriptions for antimicrobial drugs based on culture results (19, 20 ).
It is unclear whether failure to modify inaccurate risk perceptions after risk counselling reflects inadequacy of the communication process itself, and/or difficulties on the part of counselled persons in comprehending or remembering the information given.
Secondly, failure to modify the transcriptome following gene knockdown or over-expression, but where a major impact on transport is found, suggests that modulation of trafficking, and potentially other systems, within a given life stage is restricted to proteomic changes [ 117].
Important aspects are insufficient awareness and motivation of the patient, reluctance to initiate lifestyle changes, poor compliance (e.g. because of forgetfulness, tolerability problems due to adverse side effects, polypharmacy and dosing schedule, co-payments) and failure to modify therapy, when it is indicated such as use of combination therapy if monotherapy proves to be inadequate [ 51, 52].
If loading were indeed a prerequisite for sumoylation, preventing PCNA association with DNA during S phase should in turn result in a failure to be modified.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com