Sentence examples for a failure to bind from inspiring English sources

The in vivo resistance observed for the E. coli FtsZ mutations was mirrored by a decreased sensitivity to MinC in in vitro polymerization assays, and a failure to bind MinC in pull down assays [30], [31].

In A. aegypti D7 protein (GenBank ID: PDB 3DXL_A), a mutation of this position from tyrosine to phenylalanine leads to a failure to bind TXA2 analogs [ 43].

Thus, we would conclude that these patients with MTL damage are impaired at maintaining multiple items as a result of a failure to bind the different aspects of a coherent item to a distinguishable context signal.

In addition, we have shown that three naturally occurring mutations associated with a severe developmental disorder syndrome prevent secretion of CL-K1 from mammalian cells, probably as a result of a failure to bind Ca2+ during biosynthesis.

The human SCT peptide failed to significantly stimulate cAMP production by the sbPAC1 receptor which may indicate either a failure to activate the cAMP signalling pathway or a failure to bind the receptor.

The evident hierarchy of specific binding, nonspecific binding, partial chromatin binding, failure to bind mitotic chromosomes, and mitotic instability reflects the factors' developmental roles in gene activation, and suggest that re-activation of the genome following mitosis involves a replay of the network by which the cell type was established in development.

For example, disruption of the K-turn by an A1nC substitution led to failure to bind SAM, implying that a disruption of the 1b·1n pair prevents folding of the K-turn and consequent folding by the complete riboswitch, so that it cannot bind its ligand.

This is also suggested by its failure to bind to a range of lectins.

The most likely reason for the failure to bind carbohydrate is loss of Ca2+ binding.

A range of binding profiles is observed, from very restricted binding to a small set of structurally similar ligands to binding of broad classes of ligands with related terminal sugars and even to failure to bind any of the glycans on an array.

Here, we show that the biochemical characteristic of Irga6-K82A is not the expected failure to bind GTP but rather a failure to hydrolyse it once bound.