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The development of ranibizumab-related therapies, we have designed the effective drug career with engineered magnetic nanoparticles (Fe3O4) as a facile platform of ranibizumab delivery for the treatment of neovascular age-related macular degeneration.
Our results demonstrated successful rational modification of AAV2 as a targeting delivery vehicle, establishing a facile platform for precision engineering of virus-based nanoparticles in basic research and therapeutic applications.
The microfluidic chamber provides a facile platform for studying neuron-to-cell transmission of infection and viral transport in vitro.
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We therefore identified an opportunity to create a facile discovery platform enabling the characterization of existing DOT1L inhibitors, and the preparation of new compounds with improved properties.
Metabolic incorporation of d-alanine derivatives and click chemistry detection constitute a facile, modular platform that facilitates unprecedented spatial and temporal resolution of PG dynamics in vivo.
Submicron-scaled P-Aggs were constructed by mixing SA and cargo proteins labeled with a biotinylated caging reagent (BCR) and were utilized as a facile and versatile platform for the light-induced release of cargo proteins (Fig. 4).
Here, a facile and highly sensitive platform has been developed for synthesizing branched Pt nanostructures on graphene.
A facile label free, ultrasensitive platform for a rapid detection of chronic kidney disease has been fabricated.
To further simplify this structure, namely label-free strategy, we design a facile, sensitive and selective platform using a label-free beacon (AIE-MB, without fluorogen and quencher), based on aggregation-induced emission fluorogen (silole-R).
The strategy established in this study provided a facile "all-in-one" platform to integrate the drug/gene co-delivery strategy and self-sensibilization effect into one single nanocomposite for potential cancer treatment.
All the results demonstrated that direct cell-based drug assay could be performed on the stable isotope labeling assisted GS-MS platform in a facile and quantitative manner.
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