Targeted methylation of the VEGF-A promoter with the Dnmt3a-3L sc variant led to a strong silencing of VEGF-A expression, indicating that the artificial DNA methylation of an endogenous promoter is a powerful strategy to achieve silencing of the corresponding gene in human cells.
When there was an expression indicating disease activity such as "flare up," "ongoing," and "active" in medical records, we counted it as having a flare.
While Anonymous did not clearly claim responsibility, in a tweet it used the term "tango down", a CIA expression indicating an important target had been killed.
With that, Lev Sercarz rested his hands on his hips and cocked his head, with a voilà expression, indicating the demonstration was over.
The group, whose name is a Hausa expression indicating disgust with Western education, is known to have been angry over the failure to fully apply Islamic law in this predominantly Muslim region of Nigeria.
A facial expression indicating disbelief (wide eyes or raised eyebrows) or lack of approval (frown or grimace, or simply turning away) could be signs the interviewer is shutting down.
Of note, all the examined miRNAs, especially those belonging to the same stem loop, showed a quite consistent degree of expression indicating a possible parallel regulation.
In contrast to healthy tissue, tumour samples show a more complex pattern of CD44 expression, indicating a loss of splice control.
One gene, phosphodiesterase 7A had an expression pattern similar to RTL1 expression indicating a biological activity for RTL1 in muscle.
Interestingly, 37% of the oligos had a 2-fold change or more in expression, indicating a substantial difference in genetic background of these groups of tumors.
