Variants of bovine pancreatic ribonuclease (RNase A) engineered to evade the endogenous ribonuclease inhibitor protein (RI) are toxic to human cancer cells.
Glenoid chondral lesions were caregorized according to location (anterior, posterior, centered) and size (small, large, total) and treated with microfractures; in the last 11 patients, we placed a engineered hyaluronic acid membrane, Hyalograft® C, on the surface of the glenoid.
This analysis shows how the thermal transport in the near nucleation region of polycrystalline diamond can be controlled, which ultimately opens the door to create ultra-thin layers with a engineered thermal conductivity, ranging from a few W/m K to a few hundreds of W/m K.
In the described study a engineered laboratory strain of L. paracasei were used as a proof of concept for mediation of in situ neutralisation in the gastrointestinal tract.
TULIPs consist of an Avena sativa LOV2-Jα-helix domain with a peptide tag at the C-terminus of the Jα-helix (LOVpep), which binds upon light excitation to a engineered erbin PDZ (ePDZ) domain.
A third population suppression strategy involves driving a engineered homing endonuclease into a population, with the insertion site for the homing endonuclease being located within gene whose product is required for female viability or fertility (Burt 2003; Windbichler et al. 2011).
