Your English writing platform
Discover LudwigExact(2)
An element is said to be a endpoint (or stationary point) [13] of if.
Proof We show that the multifunction N X X → P ( X ) has a endpoint which is a solution of the problem (1) and (2).
Similar(57)
All other conditions of Corollary 2.5 are fulfilled and T has an endpoint A.
Although measurement of the proportions of cell types in the bone marrow that are committed to becoming RETs would prove challenging, this information would permit a better estimate of mutagenic efficiency for the Pig-a endpoint.
This study contributes to the validation of the Pig-a endpoint by comparing its responsiveness to that of the well established lacZ TGR mutation assay for the well-known mutagenic carcinogen benzo[ a]pyrene (BaP).
In contrast, the BaP doubling dose for the lacZ mutation endpoint in bone marrow is not significantly different from the the Pig-a endpoint (in both RETs and RBCs) (Table I).
The BaP doubling dose for the Pig-a endpoint in RET could not be calculated using the scoring method used for this study since no RETCD24− were detected in unexposed control animals in this study, and a measurable level of background mutant Pig-a phenotypes is required to calculate doubling dose (see Eq. 1).
Similarly, the magnitude of the lacZ response in bone marrow is approximately 25-fold higher than the Pig-a response in RETs, suggesting that the rate of conversion of adducts is slower for the Pig-a endpoint compared with the lacZ endpoint.
Moreover, 28-day repeat dose studies that test additional classes of compounds with different modes of action, as well as time-course studies to examine the persistence of mutant Pig-a phenotypes will provide further insight into the utility of the assay, and will be important steps in the validation of the Pig-a endpoint as a useful and effective in vivo somatic gene mutation assay.
Fourthly, although most studies included in this meta-analysis used all stroke as an endpoint, a few evaluated only ischaemic stroke as an endpoint.
It was as much an endpoint as a beginning, a holiday of naïveté and dumb luck before the realities of capitalism resumed.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com