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Thus, further clinical trials regarding the adequate dosing and treatment duration are needed before treatment with selenium can be recommended (DI).
Meanwhile, a systematic study is needed before practical applications.
A stepwise approach is needed before commencing large phase III RCTs.
It may therefore be the case that a minimum duration of exposure to overweight is needed before atherosclerosis is detectable, and this is unlikely to occur in pre-adolescence.
This hypothesis is consistent with the notion that a diabetes duration of at least 8 years is needed before it can be considered a coronary heart disease risk equivalent (11) and the UKPDS findings of a significant reduction in MI only after long-term follow-up (12).
Their overall conclusion aligns with a similar literature review by the Cochrane group, which found that zinc can help reduce the duration and severity of the common cold, but that more research is needed before experts can issue a general recommendation regarding its use.
Given the likelihood that prolonged or severe hypoglycemia is needed before there is a seizure, hypoglycemia detection algorithms that incorporate the duration of hypoglycemia could have lower false-positive alarm rates and thus be more clinically acceptable.
Longer durations of data are needed before the seafloor motion estimates for the Jason-2 era (2008 present) can approach this level of accuracy.
After injection of 141-mL saline (during a duration of 3 months), a 1-month static expansion phase was needed before beginning the next stage of ear reconstruction (Fig. 5).
Considering the 28-day concrete compressive strength of 41.4 MPa and a required strength at post-tension jacking of 34.5 MPa, a minimum duration of 12 days after concrete casting would be needed before the tendons could be stressed.
The authors declined to make recommendations about the optimal dose, formulation or duration of zinc use, saying that more work was needed before they could make recommendations.
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CEO of Professional Science Editing for Scientists @ prosciediting.com