Sentence examples for a durable response to from inspiring English sources

Nevertheless, patients with G3 GEP NETs did not show a durable response to pazopanib, with a median PFS of 5.8 months.

It is postulated that these clinicians might be looking for a durable response to salvage therapy, thus the extended period prior to assessment.

However, more than half of the patients with mediastinal nonseminomatous GCT failed to achieve a durable response to conventional cisplatin-based chemotherapy.

The fact that the majority of young men treated for testicular cancer have a durable response to primary treatment has resulted in the accumulation of significant data on both the patterns of relapse and the late effects of treatment.

In advanced disease, primary resistance and inadequate cell kill may be important in determining the lack of a durable response to cytotoxics, but for an individual patient's tumour there is no consistent way of determining the importance of these two factors.

Evidence of phosphorylation of HER family receptors and their downstream signaling proteins in the patients' cancers on RPMA analyses was found to not preclude having a highly durable response to capecitabine (Table 2).

Mutations in the phosphoinositide-3-kinase, catalytic, alpha polypeptide gene (PIK3CA), or amplifications of fibroblast growth factor receptor 1 (FGFR1) or zinc finger protein 703 (ZNF703) genes, did not preclude the development of a highly durable response to capecitabine (Table 1).

In patients affected with oligodendroglioma this genotype is associated with increased progression-free and overall survival as well as a better responsiveness to durable response to chemotherapy [4], [10], [11], [12].

Metastatic RCC (mRCC) rarely shows a complete and durable response to immuno- or radiation therapy [6].

In addition, long-lasting memory T cells (Box 1) are generated that can self-renew, allowing rapid expansion in the presence of the target antigen and providing a sustained and durable response to it upon re-exposure.

In a previous case of concomitant EGFR mutation and ALK translocation, the patient presented the most durable response to an EGFR-TKI and was a case demonstrating no EML4 –ALK expression by immunohistochemistry with an EML4 ALK rearrangement characterized by an isolated 3_ FISH signal [ 12].