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The phrase "a drastic decrease of" is correct and usable in written English.
It can be used when discussing a significant reduction in quantity, size, or intensity of something.
Example: "The report indicated a drastic decrease of sales in the last quarter, prompting the company to reevaluate its marketing strategy."
Alternatives: "a significant drop in" or "a sharp decline in".
Exact(56)
Future stabilization of the atmospheric CO2 content requires a drastic decrease of CO2 emissions worldwide.
This reformulation leads to a drastic decrease of the computational effort.
The use of finer pore foam structures is not convenient due to a drastic decrease of catalyst surface refreshment.
The clay nucleation activity was greatly enhanced in shear-induced crystallization and resulted in a drastic decrease of spherulite sizes.
Under high butane concentrations, the VPO system suffered from a drastic decrease of the selectivity towards maleic anhydride (MA).
An increase of Tg and a drastic decrease of ΔCp were observed when gluten was dry processed.
However, a drastic decrease of H2 productivity and a change of liquid-state metabolites were observed with the use of non-heat pretreated MFEUASBr.
Similar(4)
Notably, the sizes of the transcriptome differ significantly between the two conditions: the total copy number of mRNA under the poor condition is approximately half of that under the rich condition, largely because of a drastic decrease in a group of the most abundant mRNAs encoding ribosomal proteins.
Of significance, knockdown of TG2 caused a drastic decrease in the percentage of cells forming invadopodia, as well as in the extent of ECM degradation induced by invadopodia.
Expression of glucosinolate biosynthetic genes was slightly but significantly reduced by the single myb mutations, while the double mutation resulted in a drastic decrease in expression of these genes.
Therefore, the inhibition of the EG component may result in a drastic decrease in the rate of the synergistic hydrolysis of cellulose.
More suggestions(17)
a tremendous decrease of
a considerable decrease of
a radical decrease of
a substantial decrease of
a drastic diminution of
a drastic reduction of
a strict decrease of
a drastic fall of
a serious decrease of
a spectacular decrease of
a drastic decline of
a dramatically decrease of
a drastic change of
a drastic inhibition of
a drastic amount of
a net decrease of
a drastic degradation of
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com