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The phrase "a dramatically negative effect" is correct and usable in written English.
You can use it when discussing the significant adverse impact of an action, event, or situation.
Example: "The new policy has had a dramatically negative effect on employee morale and productivity."
Alternatives: "a severely detrimental impact" or "a profoundly adverse effect."
Exact(4)
If it fails, he said, "it would have a dramatically negative effect on American Home's stock price".
Should the club be unsuccessful in their defence, they say it "could have a dramatically negative effect on the company".
Others said that limiting advertising would have a dramatically negative effect on sports teams and pop bands that depend on food and drink company sponsorships.
Ryan Davis of GameSpot commended the game for its fundamentally solid gameplay, smooth and sharp graphics and the amount of "stuff to do", but stated that "the narrow field of vision has a dramatically negative effect on the whole experience, cross-canceling many of the game's positive traits".
Similar(56)
A culture built on the foundation of eliminating variance can have dramatically negative effects on growth and innovation.
Even supporters of these new tests have acknowledged that using them as exit exams would produce dramatically negative effects.
– 3-year intermediate profile (3-4-year follow-up): this profile is characterized by a dramatically negative perception of QoL.
Moving to a larger class had a negative effect.
In the end, any therapy that has a positive effect can have a negative effect.
When a negative effect is introduced, the diffusion curve dramatically changes its shape.
A cliff edge could have a sharp, negative effect.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com