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The phrase "a dramatic reduction of" is correct and usable in written English.
It can be used when discussing a significant decrease in quantity, size, or intensity of something.
Example: "The new policy led to a dramatic reduction of waste in the manufacturing process."
Alternatives: "a significant decrease in" or "a substantial cut in".
Exact(60)
First came a dramatic reduction of their bad loans.
The overall result being a dramatic reduction of insecticide use in NYS to manage this pest.
In spite of the economic chaos, they had succeeded in engineering a dramatic reduction of poverty.
Over the last decades, agricultural intensification has caused a dramatic reduction of grassy habitats.
Now, Lord Freud is helping oversee a dramatic reduction of welfare services, under the mantra of rationalisation and efficiency.
A dramatic reduction of normalized protein catabolic rate occurs late in the course of progressive renal insufficiency.
Recordings of hippocampal theta during movement and awake immobility revealed a dramatic reduction of theta in the lesioned animals.
When these structural changes were both introduced, a dramatic reduction of activity was observed for both N1 and N3.
Excessive flooding or dry out of the open cathode can lead to a dramatic reduction of fuel cell power.
One is that Afghan politics will be cohesive and stable enough in 2014 to bear the pressures of a dramatic reduction of foreign troops.
As expected, co-treatment with NB-598 and lapaquistat resulted in a dramatic reduction of squalene accumulation, as compared to NB-598 treatment alone (Fig. 5e).
More suggestions(17)
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com