The phrase "a dramatic disruption of" is correct and usable in written English.
It can be used to describe a significant or intense interruption or disturbance in a particular context, such as social, environmental, or technological changes.
Example: "The pandemic caused a dramatic disruption of daily life, forcing people to adapt to new routines and challenges."
Alternatives: "a significant upheaval of" or "a profound disturbance of".
MPTP injection yielded a dramatic disruption of sleep wake architecture with reduced sleep efficacy that persisted years after MPTP administration.
Very little myomesin staining could be detected in the hsp90α1 mutant embryos (Fig. 8D), suggesting that the hsp90a1 mutation could result in a dramatic disruption of M-line organization in skeletal muscles.
PTEN knockdown also causes a dramatic disruption of normal tight junction formation in adherent mammary epithelial cell cultures.
The lethality caused by hUbb over-expression was associated with a dramatic disruption of normal pupae structures and large melanotic inclusions indicative of extensive cell death.
By HH stages 19-21 (∼48 hours later), hindbrains expressing widespread ectopic murine Hoxb4 (mHoxb4) showed a dramatic disruption of morphological segmentation (Fig. 2A,A′).
Transmission electron microscope (TEM) images showed intact particles with no discernible difference in diameter, ruling out a dramatic disruption of capsid architecture.
More importantly, we had discovered dramatic disruption of BBB in S89G-DMP1 mice.
Disruption of the Hippo pathway, including major components Hippo, Salvador, and Warts, results in aberrant follicle-cell differentiation and proliferation and dramatic disruption of the oocyte anterior-posterior axis.
Conversely, Harlow et al. [ 15] showed dramatic disruption of the culturable microbiota concurrent with increased shedding of enteropathogens after administration of TMS or ceftiofur sodium in horses.
No clear trend emerged; however, que mutants consistently show the most dramatic disruption of swimming behavior compared with acc or beo mutants.
Another positive-strand RNA virus, the poliovirus, induces dramatic disruption of the Golgi with consequences for the secretory complex [ 26, 27].
