Sentence examples for a dramatic disruption in from inspiring English sources

In the absence of Netrin-dependent midline axon attraction, loss of robo2 (but not robo1 or robo3) leads to a dramatic disruption in midline crossing that is far more severe than the complete loss of Netrins, indicating that robo2 likely acts in parallel to Netrin-Fra to promote midline crossing (Spitzweck et al., 2010).

Very little myomesin staining could be detected in the hsp90α1 mutant embryos (Fig. 8D), suggesting that the hsp90a1 mutation could result in a dramatic disruption of M-line organization in skeletal muscles.

PTEN knockdown also causes a dramatic disruption of normal tight junction formation in adherent mammary epithelial cell cultures.

Transmission electron microscope (TEM) images showed intact particles with no discernible difference in diameter, ruling out a dramatic disruption of capsid architecture.

MPTP injection yielded a dramatic disruption of sleep wake architecture with reduced sleep efficacy that persisted years after MPTP administration.

The lethality caused by hUbb over-expression was associated with a dramatic disruption of normal pupae structures and large melanotic inclusions indicative of extensive cell death.

By HH stages 19-21 (∼48 hours later), hindbrains expressing widespread ectopic murine Hoxb4 (mHoxb4) showed a dramatic disruption of morphological segmentation (Fig. 2A,A′).

Dr. Sepúlveda said the findings showed that "the most dramatic disruption in primary production was for a rather short period of time".

All the pieces are in place for dramatic disruption in the government IT space.

Chronic alcohol intake is associated with dramatic disruptions in sleep and other circadian biological rhythms in both humans and experimental animals.

More importantly, we had discovered dramatic disruption of BBB in S89G-DMP1 mice.