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MPTP injection yielded a dramatic disruption of sleep wake architecture with reduced sleep efficacy that persisted years after MPTP administration.
Very little myomesin staining could be detected in the hsp90α1 mutant embryos (Fig. 8D), suggesting that the hsp90a1 mutation could result in a dramatic disruption of M-line organization in skeletal muscles.
PTEN knockdown also causes a dramatic disruption of normal tight junction formation in adherent mammary epithelial cell cultures.
The lethality caused by hUbb over-expression was associated with a dramatic disruption of normal pupae structures and large melanotic inclusions indicative of extensive cell death.
By HH stages 19-21 (∼48 hours later), hindbrains expressing widespread ectopic murine Hoxb4 (mHoxb4) showed a dramatic disruption of morphological segmentation (Fig. 2A,A′).
Transmission electron microscope (TEM) images showed intact particles with no discernible difference in diameter, ruling out a dramatic disruption of capsid architecture.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com