Sentence examples for a dramatic difficulty from inspiring English sources

This is a dramatic difficulty.

The dramatic increase in whole-genome sequencing is thus accompanied by a dramatic difficulty to reach the full biological value of the sequenced genomes with accurate identification of the protein-coding genes, as well as the nature of the functional protein products.

To say that such fidelity represented an almost impossible dramatic difficulty – this trial, like any other, was often extremely boring – would be to understate.

Relief and assessment activities have had dramatic difficulty to determine the scale of the disaster and the death toll is expected to swell.

As yet, my children have not directly experienced family break-up, the death of a parent or even the less dramatic difficulties of moving house or horrible bullying at school, but I find most children's books seem to be on these themes.

The concept of centring an opera on the casting of a statue, the great sculpture of Perseus, may be brilliant in relation to such a colourful artist as Cellini, but it presents obvious dramatic difficulties.

But you can't have such a dramatic change without difficulty".

Disulfide-rich proteins constitute one of such groups: since the reduction of thiol thiol bonds must be carried out under suboptimal conditions (to minimize the back-exchange), it frequently results in incomplete dissociation of disulfide bridges prior to MS analysis, leading to a loss of signal, inadequate sequence coverage, and a dramatic increase in the difficulty of data analysis.

His involvement in the dispute is against advice from loyalist politicians, and marks a dramatic escalation of the difficulties facing the RUC and army.

Viewed another way, the theft is simply a dramatic illustration of the difficulties that many artists have encountered after becoming involved, during the last decade, in the subway system's ambitious campaign to beautify itself.

The domestic game has been far from immune, with many clubs experiencing their share of financial difficulty and a dramatic drop in league attendances.