The phrase "a dramatic depletion of" is correct and usable in written English.
It can be used to describe a significant reduction or loss of something, often in a serious or impactful context.
Example: "The region experienced a dramatic depletion of its natural resources due to overexploitation."
Alternatives: "a significant reduction in" or "a severe loss of".
Furthermore, we detected a dramatic depletion of CLP defined as lineage-negative c-kitlo, IL-7R+ cells (manuscript in preparation).
Although both manipulations cause a large increase in extracellular 5-HT, null mutations also cause a dramatic depletion of tissue 5-HT [102], [103] and may disrupt serotonergic neuron development, as suggested by the reported decrease in serotonin cell number in null mutant mice [105] (but not rats [106]).
A dramatic depletion of CD4+ T cells occurs during acute infection in natural hosts [ 29, 30].
Strikingly, a dramatic depletion of white adipose tissue (WAT) was observed exclusively in DKO mice (−58%; Fig. 1A,B).
Of note, almost all neurons with cytoplasmic TDP-43 accumulations show a dramatic depletion of normal nuclear TDP-43.
In contrast, a dramatic depletion of lymphocytes was observed in colorectal cancer patients, which affected both lymphocyte counts (P < 0.0005) and their distribution (P < 0.0001).
Instead of burning through the susceptible population and driving itself to extinction as in a naïve population, the pathogen produces a smaller epidemic with a less dramatic depletion of individuals, which may in turn allow the pathogen to persist.
These results suggested that influenza A(H1N1 pdm09 infection induced thymic atrophy, especially of the cortex, and this was accompanied by the dramatic depletion of cortical DP T cells.
That story leads directly to the mission: The abundance of new consumers has meant the dramatic depletion of some species, especially the bluefin tuna, the Porsche of the seas.
Western blot analysis demonstrated that these compounds induced dramatic depletion of the examined client proteins of Hsp90, and accelerated cancer cell apoptosis.
Full recovery from one serious anthropogenic impact on marine ecosystems, namely the dramatic depletion of whale populations, can help to counter the impacts of another now underway the decline in nutrients for phytoplankton growth caused by ocean warming.
