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The phrase "a dramatic departure from" is correct and usable in written English.
It can be used to describe a significant change or shift from a previous state, idea, or practice.
Example: "The new policy represents a dramatic departure from the traditional approach we have followed for years."
Alternatives: "a significant shift from" or "a stark contrast to".
Exact(60)
The lab interiors are a dramatic departure from tradition.
This was a dramatic departure from standard NATO policy.
Actually, this rule is a dramatic departure from current practice.
Trump in particular has called for a dramatic departure from postwar American policy.
How's it look: It's a dramatic departure from the 2013 Lexus IS sedan.
That curriculum represented a dramatic departure from earlier approaches to education.
"The management plans were a dramatic departure from their own independent science review," she says.
It's a dramatic departure from the top-down command model associated with current building-automation systems.
"A class action is a dramatic departure from the normal rules of litigation," he said.
The management plans were a dramatic departure from their own independent science review.
It's a dramatic departure from the way this state has paid its bills before".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com