Exact(11)
Although a chemically-defined medium, supporting high growth rates, is available for L. lactis (Poolman and Konings, 1988), we noted a dramatic decrease in the expression levels of several proteins once the standard complex broth was changed for CDM.
Consistent with a bacterial growth arrest, we also noticed a dramatic decrease in the expression of cell wall components including several Sca family proteins (Sca0, Sca1, Sca4, Sca5 and Sca10).
At E18.5, we observed a dramatic decrease in the expression of KCC2 in mutant cortex.
Loss of PAX8 expression was also accompanied by a dramatic decrease in the expression of both MET and RON but not EGFR tyrosine kinases.
The results of Western blot demonstrated clearly that SACC-M-WJ4 cells showed a dramatic decrease in the expression of XTLY-I protein (Fig. 4A-B & Table 2).
In contrast, in colon tissue from ZnR/GPR39 KO mice, we found a dramatic decrease in the expression of tight junction proteins, occludin and ZO-1.
Similar(49)
In the present study, we observed a dramatic decrease in the protein expression levels of MET and RON.
Knock-down of the small GTPase rab-5 also leads to a dramatic decrease in the amount of apl-1 expression in neurons, suggesting that trafficking from the plasma membrane to the early endosome is important for apl-1 function.
Western blot analyses of Paigen diet-fed animals (Fig. 1) showed a dramatic decrease in the levels of SR-BI protein expression in the livers of PDZK1/apoE dKO animals when compared to apoE KO animals.
In fact, over-expression of SFRS3 causes a dramatic decrease in the levels of IL-1β secretion after 24 hrs of THP-1 cell challenge with PFA-fixed E. coli (Figure 3G).
As shown in Figure 6B, the overexpression of RND3 resulted in a dramatic decrease in the Notch-binding nucleotides pulled down from the cells, and this decrease was furthered when RND3 expression was increased.
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