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Gli1 is known to be a downstream target of SHH signaling.
Taken together, these results support that CTGF is a downstream target of Yap1 in β-cells under palmitate treatment.
Receptor for Activated Kinase C-1 (RACK1) was identified as a downstream target of OsRac1 (Nakashima et al 2008).
Clones were picked, amplified, and screened by alkaline phosphatase (ALPL; a downstream target for BMP-2 signaling) staining [35].
In fact, MYB appears to be a downstream target of c-Myc.
In this context Fetuin B (Fetub) was identified as a downstream target of Pthlh.
It has been reported to regulate c-MYC expression as a downstream target of TIP30 [85].
Altogether, these results provide evidence that L1TD1 is a downstream target of Nanog.
ELK is a well-established substrate and a downstream target of ERK [29].
cMyc is a downstream target gene in the STAT3 signalling cascade.
PU.1 is a downstream target of Akt1 in the B-cell lineage [36].
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