Your English writing platform
Discover LudwigExact(2)
Using controlled simulation experiments we demonstrate that a bottleneck shift to a station upstream of the assumed bottleneck has a negligible effect on DBR performance while a downstream shift is detrimental to performance.
In some cases this causes a downstream shift of the transcriptional start site in the targeted gene, suggesting that TAL effectors might have a similar function of TATA-binding proteins [ 6- 10].
Similar(57)
Therefore, MPA phenotypes of combinations of GTF alleles and Pol II mutants appeared additive or suppressive depending on the nature of the allele class: when upstream shifting alleles were combined, MPA sensitivity was exacerbated; when an upstream shifting mutant was combined with a downstream shifting mutant, MPA sensitivity was alleviated.
Reasonable comparison can be obtained only with an arbitrary downstream shift of 20 mm in the origin of the predictions from the burner exit.
A weak downstream shifting allele, sua7 -70A5, showed negative but weaker interactions with Pol II LOF alleles.
This downstream shift has important consequences for the possible size of the Io intrinsic field.
"Tilt" will help you grasp the global nature of this downstream shift and its profound implications for your strategy and your organization.
Alleles of rpb2 and rpb9 were shown to suppress the downstream shift effect and cold temperature sensitivity of certain sua7 alleles (Sun and Hampsey 1996; Sun et al. 1996; Chen and Hampsey 2004).
Previous analyses showing that distinct classes of TSS mutant exist in yeast (upstream and downstream shifting), supporting a scanning model for identification of TSSs.
Considering the established role of ATRX as an epigenetic regulator, we hypothesized that its inactivation induces glioma-relevant phenotypes by way of chromatin remodeling and downstream shifts in gene expression.
For that purpose, spatially varying ice flow velocities from the 2000/2001 MEaSUREs Greenland Ice Velocity Map5,23 were interpolated onto each of the five ice base profiles used for the plume model (Supplementary Fig. 2), and integrations for each profile were repeated with eleven different starting points from the grounding line and downstream, shifted in 1-km steps.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com