Sentence examples for a downstream role from inspiring English sources

Gazprom is expected to name an American partner for the Shtokman project soon; in return, it will want a "downstream" role in America, of just the sort that has been worrying the Europeans.

Thus, Bim does not appear to play a downstream role in promoting death of Mcl-1-deficient thymocytes.

Enhanced Dvl2 level did not significantly interfere with stress mediated phosphorylation of eIF2α (Fig. 3A), suggesting a downstream role for Dvl2 for impairment of SG assembly.

It should be pointed out that NAC had a minimal effect on mitochondrial morphology, thus suggesting a downstream role for ROS in Os-induced cell death.

However, Asrij does not play a downstream role in the JAK-STAT pathway in maintaining the HSC population, as stat92e depletion in lymph glands along with forced expression of Asrij leads to precocious hemocyte differentiation, thereby disrupting hemocyte homeostasis.

We found that dominant-negative Rac1 and constitutively-active RhoA reversed the effect of Dvl2 on SG assembly, suggesting that Rac1 and RhoA play a downstream role (Fig. 2C,D).

In contrast, Bax has a more downstream role in effecting apoptosis, which perhaps explains its more predictable cytotoxicity on tumor cells [ 126*].

While the pathogenesis of AD involves the extraneuronal deposition of the amyloid-beta peptide and phosphorylation of intraneuronal tau proteins [ 2], loss of synapses is thought to play an important downstream role in the process of cognitive loss [ 3, 4].

It was found that Na+/Ca2+-exchanger (NCX -mediated Ca2+ efflux was sigNCX -mediatedhanCa2+by fleffluxde and that the effects of flecainide on wase frequency could be reversignificantlyng [Na+]o, suggenhancedn important downstream role for NCX function.

However, it has been hypothesized that these serve a downstream 'command' role, relaying information from integration/higher-processing centers to motor centers in the VNC [ 26,53 ].

This poses an issue when trying to ascertain the downstream role of this immunomodulatory peptide.