Sentence examples for a downstream reduction of from inspiring English sources

Furthermore, p-ERK1/2 downregulation is followed by a downstream reduction of c-Myc, which might contribute to the aforementioned G1 arrest.

Suppression of these genes predicts a downstream reduction in the early formation of neural cells.

While GIs have been mentioned in the literature for stormwater management (Dietz and Clausen 2008; Elliott and Trowsdale 2007; Hood et al. 2007; Bedan and Clausen 2009) there is little research that studied GI impact on the downstream reduction of stream bank erosion in urban areas (Burns et al. 2015; Jia et al. 2015).

Since CCT-eta is shown herein to be essential for α-SMA protein accumulation, we posit that reduction of CCT-eta regulates fibroblast motility and contractility through its downstream reduction of α-SMA.

Moreover, downregulation of the deubiquitinase Usp9x by pemetrexed results in downstream reduction of myeloid cell leukemia 1 (Mcl-1) expression.

Other studies have implicated increases in HO-1 as a downstream mediator of Hif1-dependent reduction in cardiac ischemia reperfusion injury [184].

For almost all downstream applications a substantial reduction of the tar concentration is required.

We noted in cartilage derived from old donors that there was primarily a reduction in the expression of some key Wnt signalling genes plus an increase in the Wnt antagonist DKK1 and a reduction in RUNX2, a downstream target of Wnt.

As far as p75NTR signaling is concerned, it is expected that the lower binding affinity of hNGFR100E mutants for p75NTR results in a reduction of downstream signaling.

Further investigation found a reduction of downstream transcriptional targets of HIF-1 α, glucose transporter 1 (GLUT1), and lactate dehydrogenase (LDH).

We next tested a gain-of-function mutation in the downstream kinase akt-1 [ 22] and a reduction-of-function mutation in daf-18 [ 23], the PIP3 3-phosphatase PTEN.