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This new transposon is 2931 bp in length and encodes two active forms of transposase, a 708-amino acid-long transposase and a short 576-residue-long transposase translated from a downstream in-frame initiation codon.
A downstream in-frame AUG may allow for the expression of a truncated protein of 397 aa, compared to the 437-aa CL Brener protein.
Insertion of this 47-nt cassette introduces a frameshift that gives rise to truncated ADAR2 proteins, unless a downstream, in-frame translational initiation codon is being used.
This directs the interactions between the D153 residue and DNA also in a downstream sense (in a congruent way with which occurs for the R160 set of interactions).
This study identifies CXCR4 as a downstream component in Wnt5a pathway in ES.
Therefore, the first intron of a downstream gene in an operon, will not be the first intron in the transcript.
mTOR is a downstream mediator in the PI3K/Akt signalling pathway, which plays a critical role in regulating basic cellular functions.
mTOR is a downstream mediator in the PI3K/Akt signaling pathway and plays a critical role in cell survival.
The hatchery is also a good place to start a downstream hike in the Capilano River Regional Park, part of the Greater Vancouver Regional District (604-224-5739; www.gvrd.bc.ca/parks).
SSA Hsp70s bind mostly post-translationally to a more restricted subset of newly translated polypeptides, suggesting a downstream function in the folding pathway.
The general pattern for the Rhône network shows a downstream increase in FW related to the concept of river continuum.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com