Sentence examples for a downstream event from inspiring English sources

As expected, uttroside B induced cleavage of PARP, a downstream event of caspase activation.

MLKL translocation as a downstream event of RIP3 was required in matrine-induced necroptosis.

These data together indicated that MLKL translocation to plasma membrane, as a downstream event of RIP3, was critical for matrine to induce necroptosis.

Translocation of mixed lineage kinase-domain like (MLKL) from cytoplasm to plasma membrane as a downstream event of RIP3, as well as the increased production of reactive oxygen species (ROS) by RIP3/MLKL, was critical for matrine to induce necroptosis.

Additionally, we showed that ATRA inhibited NRF2 activation as a downstream event of ALDH1 suppression and in particular, we demonstrated that the effect of ATRA on ALDH1A1-NRF2 axis was restricted to ALDH1-high cells.

Down-regulation of Cacnb3 expression did not rescue placental hyperplasia in a model of interspecies hybrid placentas, which indicates that up-regulation in the hyperplastic placentas is a downstream event.

In contrast to the approaches presented above, the method proposed by Chung et al. targets a specific downstream event in a fibrotic cascade.

Together, these results suggest that proteolytic activation of PKCδ may be a critical downstream event in the degenerative process of Parkinson's disease.

Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway.

Transcriptional responses are a relatively downstream event from phosphorylation in signaling cascades.

As the epimutation of LOC149837 is present in all seven analyzed premature aged samples (including the mutation driven phenotypes, Fig. 3B), we suggest the differential promoter hypomethylation to be a common downstream event with crucial function in disease onset.