Sentence examples similar to a downstream aging from inspiring English sources

Another possible mechanism may be that reducing insulin/IGF-1 signaling leads to down-regulation of certain downstream aging-promoting signaling pathways.

This leads to a decreased expression of the elt-3 GATA transcription factor in old age that causes down-regulation of many downstream age-regulated genes.

In our study, we found reduced expression of ARHGEF2, a downstream effector of EGFR signaling, in fibroblasts from aged donors.

S6K is a downstream target of rapamycin (mTOR) pathway, a key modulator of aging [ 75].

These findings illustrate an evolutionary conserved epigenetic mechanism that determines the rate of aging downstream of mitochondrial perturbations.

Restoring the down-regulated levels of Survivin (an Inhibitor of Apoptosis protein and a downstream target of Wnt), results in enhanced NPC proliferation in the aging brain.

When AGEs bind to their receptor, RAGE, ROS are released as a downstream byproduct [25].

We reviewed the role of OS and its downstream signaling in aging eyes.

We see the clear downstream consequences during aging emerging in the proteome, including metabolic shifts, stoichiometric loss, aggregating proteins, and protein overproduction.

Finally, AGEs are able to bind and activate a range of receptors, which then trigger a downstream cascade of pathogenic mediators.

But that is just a "downstream" measure.