Sentence examples for a downstream activity from inspiring English sources

These extra meanings are typically loosely formulated, in which case it is not possible to validate the feature-based model to ensure that it provides a correct representation for a downstream activity such as process planning.

Altered expression of the mammalian target of rapamycin complex 1 (mTORC1), a key regulator of cell metabolism and a kinase whose downstream activity is associated with phosphatidylinositol 3-kinase (PI3-K) signaling pathways, significantly alters the fate of adult stem cells.

20 A pulse of glucocorticoid triggers a pulse of glucocorticoid receptor binding which then triggers a pulse of downstream activity.

In contrast to A549 cells, YFP-β1 did not cotranslocate in CHO cells (data not shown) suggesting that they do not contain translocating γ subunits at concentrations that are likely to have an effect on downstream activity.

After binding IGF ligand, IGF-1R undergoes autophosphorylation, inducing various substrate activations and downstream activity.

If you are an integrated oil company, this downstream activity nicely balances out the drilling cycle.

We thus devised a function f([ MITF],[ MITF p 73],[ MITF p 409],[ MITF p p]) to map the amounts of the different phosphorylation states of MITF to a downstream transcriptional activity.

In addition, an association was not observed between PyMT downstream activity and number of metastases (Additional file 5, panel c).

Rac downstream activity, which counteracts the RHOA-ROCK axis,32 was blocked by the PAK inhibitor IPA3.

In this regard, reduced ovarian ER-β mRNA levels may contribute to altered Ob-Rb mRNA levels and downstream activity.

18F-FDHT, a ligand that targets the ligand-binding domain of AR, assesses receptor occupancy but not downstream activity.