Sentence examples for a downregulated expression of from inspiring English sources
On the other hand, NTERA2 cells showed a downregulated expression of p53 when transfected with the specific shRNA, which was even more evident when this cell line was treated with cisplatin (Figure 1C).
A downregulated expression of miR-125b was found in OSCC-derived cell lines and OSCC samples.
Interestingly, a longer incubation period, that is, 8 and 20 h, resulted in a downregulated expression of maspin by PMN.
However, another study showed a downregulated expression of miR-27b in both the tumor tissues and the plasma of OSCC patients [ 74].
Therefore, we hypothesized that the increased T levels in female placentas form the n-3 LCPUFA intervention group might be due to a downregulated expression of CYP19A1.
The authors also investigated the reason for downregulation of miR-494 in PDAC and found that loss of Smad4 expression in PDAC resulted in a defect in the TGF- β signaling, which ultimately caused a downregulated expression of miR-494.
Interestingly, a downregulated expression level of CASP9 was observed in DMD iPSC-CMs when compared with control iPSC-CMs (Fig. 4C, middle panel; supplementary material Fig. S4), indicating that the cleavage of UC-CASP3 in DMD iPSC-CMs could be possibly mediated by other caspase(s).
Gene expression is plotted with each gene as a unique horizontal bar and is expressed as log2; therefore, compared to sham, a fold change of 0.5 represents a downregulated expression at an absolute fold change of -2.
Resveratol, a dietary polyphenol, downregulated expression of EMT master genes Zeb1, Snail and Slug and impaired CSC self-renewal capacity, tumor growth and invasion in a mouse model of pancreatic ductal adenocarcinoma [144].
When we assayed for the PDGF ligands, we found significantly elevated levels of PDGF-B and downregulated expression of PDGF-A as compared with the bm-MPCs.
A first attempt in an adaptation process generated an E. coli mutant EMFR9 with downregulated expression of yqhD (Miller et al. 2010).
