The phrase "a double mechanism" is correct and usable in written English.
It can be used to describe a system or process that operates through two distinct methods or components.
Example: "The device operates using a double mechanism that enhances its efficiency and reliability."
Alternatives: "a dual mechanism" or "a twofold mechanism".
Such a double mechanism thus constitutes a very effective firewall.
The occurrence of a double mechanism of action could plausibly be a distinctive feature of the mode of action of 4-oxo-4-HPR, since these two unrelated pathways were found in cancer cell lines of different histotypes (ovarian, breast, cervical carcinoma and neuroblastoma).
Moreover, 4-oxo-4-HPR-induced cell cycle arrest and the formation of multipolar spindles were independent from the ROS-associated signaling cascade, not only in ovarian but also in breast, cervical and neuroblastoma cancer cell lines, revealing the distinctive feature of 4-oxo-4-HPR to have a double mechanism of action.
The finding of a double mechanism underlying anticancer activities of 4-oxo-4-HPR provides an explanation of the ability of 4-oxo-4-HPR to be more potent than the parent drug and to be effective also in 4-HPR-resistant cell lines (i.e. A2780/HPR cells) [12].
This realizes a double mechanism of transmission, in which M and F mtDNAs are inherited uniparentally.
Both compounds affect angiogenesis through a double mechanism of action: reduction in VEGF production by tumour cells and concomitant direct inhibitory effect on endothelial cell functions (Guba et al, 2002).
We explain these results through a proposed double mechanism of interfacial modification between the HDPE matrix and the TPS dispersed phase.
The heritability of the green phenotype at 8 10°C [ 3], and the higher adenine methylation rates within the transposase and helicase genes (current study), suggest the existence of a coincidental double mechanism: strain selection and the regulation of new active genes by adenine methylation.
One possibility is a double displacement mechanism via a covalent mechanism, analogous to that used by glycoside hydrolases.
The rock salt constitutive model accounted for the primary and secondary creep through a combination of a power law and the double mechanism law.
The position mechanism implements the kinematic characteristics of a double parallelogram mechanism driven by a cable, which can decouple the position and posture of the slave manipulator.
