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To investigate the biochemical basis for the distinct functions of Sox2 and Sox17, we solved the crystal structure of the high mobility group domain of Sox17 bound to a DNA element derived from the Lama1 enhancer using crystals diffracting to 2.7 Å resolution.
Finally, the Smith-Waterman algorithm has been employed to compare the logs (every system call ID is being used by the algorithm as a DNA element).
Introduction of potassium ions induces the guanine-rich tracts in the duplex precursors to Hoogsteen base pair, creating a DNA element called a guanine quartet.
The Entamoeba Dnmt2 homologue binds in vitro to EhMRS2, a DNA element containing the consensus scaffold/matrix attachment region (S/MAR) bipartite recognition sequences suggesting that Dnmt2 like molecules can interact directly with DNA [17].
A DNA element derived from the pOPI3CAT expression vector containing three symmetric lac operator (lacO) binding sites recognized by the lac repressor (lacI), within a SV40-derived intron, was subcloned between the transcription start site of the endogenous Vav-gene and the multiple cloning site (MCS) of the HS21/45 VavP-transgenic vector.
transposable genetic element A DNA element that can move from one location in the genome to another.
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RA binding to RAR/RXR heterodimers bound to a regulatory DNA element leads to a cascade of events resulting in recruitment of transcriptional co-activators and initiation of transcription [35], [37].
The palindromic repeats found in the Volvox and Pseudendoclonium chloroplasts have been suggested to descend from a selfish DNA element carried by a mobile intron involved in interorganellar lateral DNA transfers (Pombert et al. 2005; Smith and Lee 2009).
However, unlike in the case of the β-globin insulator, we were unable to isolate a small DNA element that functioned as an enhancer blocker in our study system.
The protein encoded by the T gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site.
This finding delineates a region of 79 bp (−393 to −315) that presumably contains a critical DNA element(s).
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