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SEUSS (SEU) is a member of a family of transcriptional co-regulators that controls a diversity of developmental events in Arabidopsis thaliana [ 1, 2].
Detailed gene regulatory networks (GRNs) in a number of invertebrate species have provided an unprecedented global overview of the genetic program controlling development in sea urchin, Drosophila, and C. elegans[ 1- 4] and have revealed a number of important and conserved regulatory cassettes employed in a diversity of developmental contexts [ 5].
Members of the Sox family have been reported to regulate a diversity of developmental processes, including the maintenance of pluripotency of embryonic stem cells (ESCs; Sox2), testis determination (Sry), chondrogenesis (Sox5, Sox6, Sox9), as well as the development of the cardiac and lymphoid systems (Sox4), lens (Sox1 and Sox2), neural tissues and the brain (Sox1, Sox3, Sox11, Sox14, Sox21).
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Further investigation of 14 α-like (Abpa) and 13 β- or γ-like (Abpbg) undisrupted gene sequences revealed a rich diversity of developmental stage-, sex- and tissue-specific expression.
These context-specific networks demonstrate that highly specific biological hypotheses can be generated for a diversity of individual processes, developmental stages, and plant tissues in A. thaliana.
Individuals who develop SSD experience a diversity of subtle premorbid developmental deficits and risk exposures, spanning the prenatal period through early adolescence.
aFive plants per experiment; bTen plants per experiment, except six plants for F012; cLineages used for cDNA library construction As summarized in Table 3, 16 cDNA libraries representing a diversity of tissues and developmental stages were constructed from four aphid lineages (USDA, 2001 12, F001, and G006).
These species represent not only key nodes in the angiosperm phylogenetic tree and its sister group (gymnosperms), but also a diversity of reproductive structures and developmental patterns.
Pleiotropic responses to single gene lesions recruit a diversity of transcriptome elements that dictate developmental progress, and such dynamic expression changes creates a complex network that make identification of inconspicuous gene relationships challenging.
Eric Harris Davidson was a unique and creative intellectual force who grappled with the diversity of developmental processes used by animal embryos and wrestled them into an intelligible set of principles, then spent his life translating these process elements into molecularly definable terms through the architecture of gene regulatory networks.
However, it should be noted that these taxa represent a sampling of relatively derived taxa, and do not represent the full diversity of developmental modes.
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