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Global gene expression profiling of MG-treated macrophages revealed a diverse spectrum of functions induced by MG, including apoptosis and immune response.
The family of insulin-like growth factor binding proteins (IGFBPs) has been shown to have a diverse spectrum of functions in cell growth, death, motility, and tissue remodeling.
Differentially expressed proteins identified in the current study covers a diverse spectrum of functions including transmission across chemical synapses, antigen processing and presenting, neurotransmitter release cycle and interferon signaling.
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Recent studies provide evidence that miRNAs are abundant in the liver and modulate a diverse spectrum of liver functions [ 6].
There is emerging evidence that microRNAs (miRNAs) can modulate a diverse spectrum of cardiac functions through their ability to remodel cardiac transcriptional circuits (reviewed in [ 5– 7]).
Based on the functional annotations of the CRP target genes that we have predicted in this study, CRP seems to be involved in a rather diverse spectrum of functions in cyanobacteria (Table 4) as summarized below.
The ECS regulates a diverse spectrum of physiological processes, including motor function, pain, appetite, cognition, emotional behavior, and immunity.
Upon activation, Akt phosphorylates a diverse spectrum of substrates known to regulate cellular functions related to cell cycle progression, cell growth and proliferation, cell death/survival and cell differentiation [3].
With nesprin-1 UTRs more randomly scattered along its gene, the combinations of nesprin-1 5′UTRs and 3′UTRs are potentially unlimited and would allow generation of a diverse spectrum of SR variants with specialised tissue specific scaffolding functions.
Many studies have also hitherto demonstrated that some of the identified ISGs can exert broad antiviral activities against a diverse spectrum of viruses, whereas other ISGs may have virus type-specific functions.
Consequently, mutations affecting the function of MICOS are responsible for a diverse spectrum of human diseases.
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