This group prefers to model evolution as a diverse set of processes acting on the histories of diverse kinds of entities generating, finally, a diversity of overlapping and cross-cutting patterns, corresponding to different evolutionary outcomes.
We need an ontology that can represent a diverse set of processes including, for example, as well as phylogenetic relations, interactions that stabilise or destabilise the interacting entities, spatial relations, ecological connections, genetic exchanges, etc.
HIA describes a diverse set of processes along with a range of qualitative or quantitative methods to identify the health effects of public policy decisions, which, in turn, help to shape policy to promote and protect health (Kemm and Parry 2004; Quigley et al. 2006).
In this article we consider microbial entities as more or less stabilised functional wholes, and sketch a network-based ontology that can represent a diverse set of processes including, for example, as well as phylogenetic relations, interactions that stabilise or destabilise the interacting entities, spatial relations, ecological connections, and genetic exchanges.
GO enrichment analysis of their functional subnetworks suggests, both in L. rhamnosus GG (Table 3) and C. jejuni NCTC 11168 (Additional file 2: Table S2), a link between PG biosynthesis and a diverse set of processes, such as the regulation of cell shape, cell cycle and response to antibiotics, in agreement with the well-known functions of PG.
However, Fyn is involved in a diverse set of physiologic processes important to normal function, and disrupting some of these processes could potentially have unintended consequences.
Nerve growth factor (NGF), a neurotrophin, modulates a diverse set of physiologic processes in the nervous, immune, and endocrine systems.
Lectins are ubiquitous proteins in plants and play important roles in a diverse set of biological processes, such as plant defense and cell signaling.
Protein SUMOylation is a dynamic post-translational modification shown to be involved in a diverse set of physiologic processes throughout the cell.
Through the activation of different signaling pathways, S1P mediates a diverse set of biological processes, acting as both an intracellular second messenger and as an extracellular ligand for specific cell surface G protein-coupled receptors, S1P1 S1P5 [21].
