Further analysis revealed that N-terminal PrsW domains are associated with a diverse array of toxin domains, including several distinct versions of the restriction endonuclease superfamily, mainly in Gram-positive bacteria.
We have presented a phylogenetic survey of myotubularin genes across a diverse array of eukaryotes, including distribution, domain architecture, and inferred evolutionary history.
In the classical polymorphic toxins ZU5 autopeptidases are found in association with a diverse array of nuclease and peptidase toxin domains.
Our earlier study had shown the versatility of the SUKH and SuFu domain immunity proteins in interacting with a diverse array of structurally and mechanistically distinct toxin domains [ 17].
Thus, we also considerably extend their structural and mechanistic diversity to include a diverse array of peptidases, ADP ribosyltransferases, glycosyltransferases, kinases, membrane perforators and domains with several other activities.
A diverse array of problem types characterizes the domain of evolutionary biology, including quantitative and probabilistic problems relating to sub-cellular elements (e.g., alleles, base pairs, and other genetic elements); macroevolutionary scenarios such as adaptive radiations (Catley et al. 2011); and genomic and bioinformatic models (Nehm and Budd 2006).
These proteins possess a diverse array of structurally and functionally distinct RNA-binding domains such as RNA recognition motifs (RRM), KH domains, RGG boxes, zinc finger, double-stranded RNA-binding domain, etc [ 1].
On the other end of the scale are some chromalveolate lineages, in particular the stramenopiles, and, to a lesser extent, also the metazoa, which have combined the FH2 domain with a diverse array of other conserved modules.
These domains are involved in a diverse array of cell functions including adhesion, migration, differentiation, apoptosis, morphous change, haemostasis and reparation of damage, etc.
Our studies revealed that two-thirds of the CSCs function as cis-regulatory enhancers that regulate gene expression in a diverse array of spatiotemporal aspects, which taken together reflect pdm expression domains.
The SH2 domain is the classic archetype for the large family of modular protein interaction domains that serve to organize a diverse array of cellular processes [ 5, 6].
