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Phosphoinositides function in a diverse array of cellular activities.
The WW-containing oxidoreductase (WWOX) tumor suppressor participates in a diverse array of cellular activities by virtue of its ability to recognize WW-binding protein 1 (WBP1) and WW-binding protein 2 (WBP2) signaling adaptors among a wide variety of other ligands.
PtdIns 3-kinase regulates a diverse array of cellular activities such as cell growth, survival, cytoskeletal changes and trafficking of intra-cellular organelles.
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cAMP mediates a diverse array of cellular responses by activating PKA.
Although USP11 has been shown to interact with a diverse array of cellular proteins (Bouwmeester et al, 2004; Yamaguchi et al, 2007), its de-ubiquitination activity has only been shown for a few substrates (Ideguchi et al, 2002; Lin et al, 2008).
Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases.
AMPK regulates a diverse array of cellular processes involved in diabetes, inflammation, and carcinogenesis such as cell metabolism, proliferation, differentiation, and apoptosis19,20.
Membrane proteins are involved in a diverse array of cellular functions and part of many important metabolic pathways.
In addition, we identified a group of genes involved in a diverse array of cellular functions including: BZW2, H2AFY, SFRS3, NAP1L1, NOLA2, UBE2D2, CCNG1, LIFR, FABP3, and EDG1.
The primary physiological role of the RyR is to provide a ligand-regulated pathway for the release of stored Ca2+ to regulate a diverse array of cellular processes.
Extensive studies have revealed that EPAC1-mediated cAMP signaling is highly coordinated spatiotemporally through the formation of dynamic signalosomes by interacting with a diverse array of cellular partners.
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