Sentence examples for a divergent function in from inspiring English sources

Then, we demonstrate that Dmrt2b contributes to a divergent function in somitogenesis through Hedgehog pathway, because Dmrt2b knockdown reduces target gene expression of Hedgehog signaling, and also impairs slow muscle development and neural tube patterning through Hedgehog signaling.

Together, these data indicate that fish-specific duplicated dmrt2b contributes to a divergent function in somitogenesis through Hedgehog pathway and maintains the common function for left-right asymmetry establishment.

While C. dubliniensis crz1/crz1, crz2/crz2, and crz1/ crz1 crz2/ crz2 double mutants grew similarly to wild-type in the presence of TM, the C. albicans crz1/crz1 mutant exhibited attenuated growth that was intermediate between wild-type and calcineurin mutants (Figs. 1 and 2), indicating a divergent function of Crz1 in ER stress responses in both Candida species.

It is also a limitation that the findings presented in this study may not be uniformly true for a wide variety of cancer cells, considering a divergent function of TGF- β1 in modulating the malignant phenotype of cancer cells (Desruisseau et al, 1996; Tuxhorn et al, 2002).

Moreover, some duplicated paralogous genes showed divergent function in the evolutionary process, even though the reasons for expression divergence of the duplicated genes in many gene families remain unclear.

The duplicated ortholog pairs of BdMAPK cascade kinase genes revealed their convergent or divergent function in the process of evolution.

Base on the regulation network, we found that most of duplicated BdMAPK cascade kinase gene orthologs showed their convergent function, whereas few of them developed divergent function in the evolutionary process.

The network of co-expression regulation showed the most of duplicated BdMAPK cascade kinase gene orthologs demonstrated their convergent function, whereas few of them developed divergent function in the evolutionary process.

Divergent functions in duplicates might help permanent preservation of the genes.

The data suggest fish-specific duplicated genes Dmrt2b and Dmrt2a play overlapping roles in establishment of Left-Right asymmetry and divergent functions in somitogenesis, which Dmrt2b contributes to Hedgehog pathway.

c-Raf and MAP3K8 are two serine/threonine kinases which are associated with cellular transformation, but which are suggested to have divergent functions in cellular physiology despite their high sequence homology.