Sentence examples for a distribution study from inspiring English sources
The doses of BDE-47 resulting in impaired learning and memory and reduced LTP measured in hippocampal slices were estimated (using a distribution study; Staskal et al. 2006a) to result in peak brain concentrations of approximately 1 μM, whereas acute toxic effects of BDE-47 were seen in vitro only at concentrations ranging from 3 to 20 μM (Coburn et al. 2008; Dingemans et al. 2007.
Recently, a paclitaxel nanosuspension formulation was evaluated in a manuscript describing a pharmacokinetic study in rats and a tissue distribution study in mice [41].
A tissue distribution study was carried out on an extra group of 24 male Wistar rats with chemically-induced HCC.
In addition, a radiolabeled distribution study with dogs was carried out and an increased distribution of tenofovir to tissues of lymphatic origin compared to the commercially available prodrug tenofovir DF (Viread) was found.
Similar results were obtained recently in a tumor distribution study by Glatt et al. with anti-CD44 antibodies of different affinities (Glatt et al., 2016).
From a particle distribution study, it is shown that surface modification with longer carboxylic acid would give better dispersion of the particles in the matrix.
For example, a tissue distribution study showed that the lung-to-blood ratio was 5, 10, and 15 for antibodies of anti-Thy-1.1, anti-ACE, and anti-ICAM-1, respectively (Danilov et al., 2001).
In a monkey distribution study with rituximab, the levels of peripheral blood B cells were already depleted by >94% 2 days after the first dose and 9 days after the second dose.
A tissue distribution study indicated that the fluorescent ligand preferentially accumulates in tissues that express high levels of the receptor in vivo.
Thirty Wistar rats (15 female, 15 male; weight 200±20 g) were randomly assigned to five groups (6 rats/group) to carry out a tissue distribution study.
Two sampling locations were selected, Ormesta (WGS84; 59°15°16′48′′E5°16′48′′E) and Vattenparken (WGS84; 59°15°15′00′′E5°15′00′′E), on the basis of a geographic distribution study of human tularemia cases in the area (13 ).
