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The result showed a distinctive decrease of pSmad2 and pSmad3 levels in the Tg chondrocytes, suggesting that ΔTβRI acts dominant-negatively and can effectively inhibit TGFβ canonic signaling (Figure 1H).
As predicted, a distinctive decrease of pSmad1,5 level were detected in Smad1cKO/cKO chondrocytes, and the decreases is more pronounced in Smad1cKO/cKO Smad5+/− mice, suggesting that lost of Smad1 and Smad5 allele effectively inhibit BMP canonic signaling (Figure 1H).
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The increase in cell count number by 200% causes a distinctive decrease in refractive index and absorption coefficient values.
The distinctive decrease of TRF lengths in skin and muscle from WS individuals also indicated a tissue-specific effect of WRN on telomere maintenance.
This decrease is a distinctive feature of CCl4 which rapidly increases the triglyceride accumulation in the liver due to a failure in their secretory mechanisms [ 31, 39] and also increased uptake of triglycerides into the liver.
In EOG, a decrease in the Arden ratio is a distinctive feature of VMD [ 14], due to a defect in Ca2+ activated Cl- channels of the RPE basolateral membrane that expresses bestrophin.
Seasonality, with an increased incidence during winter and a decreased incidence during summer, has been considered a distinctive feature of SIDS.
A distinctive hallmark of HF is that of autonomic disturbance, that is, increased sympathetic activity and decreased parasympathetic tone.
Blastocyst, a distinctive stage of a mammalian embryo.
Circumcision was a distinctive mark of the cult community.
Fire plans are a distinctive feature of Australian life.
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