Exact(1)
We propose that CHMP2B missense mutations associate with ALS and demonstrate that these mutations give rise to a distinct clinical and neuropathological phenotype, cause a distinctive alteration in the motor neuron transcriptome and disrupt cellular pathology, compared to controls.
Similar(59)
A cell sub-population is defined as a group of cells with a distinctive chromosomal alteration (numerical or structural) at a specific area of the tumor.
The results clearly demonstrate that exposure of mice to a single dose of ENU can cause distinctive alterations in miRNA expression at the different sampling times after the ENU treatment (Table 1 and Figures 1, 2, 3 and 4).
Even when these practices are no longer strictly necessary for preservation, the distinctive alterations in taste that they produce have cultivated a continuing demand for fish preserved in these ways.
Using FCM, we characterized two distinctive alterations in colorectal tumors.
Classical homocystinuria is an autosomal recessive disorder caused by cystathionine β-synthase (CBS) deficiency and characterized by distinctive alterations of bone growth and skeletal development.
These distinctive alterations in the symbiotic partners ensure the effective exchange of water and nutrients from the fungal partner to the carbohydrates of the plant [ 35].
The selection of the C/acC combination in our classification approach appears in analogy to the results of our previous work with cell culture supernatants, which showed distinctive alterations in the excretion of cytidine in breast cancer cells [ 30].
The distinctive alterations in ventricular size [ 83, 84] and CSF dynamics associated with INPH have been shown to alter the concentration gradients of monoamine metabolites in CSF of hydrocephalus patients [ 85, 86] and could alter the concentrations of other CSF biomarkers in unpredictable ways.
Chromatin remodeling might then involve making only subtle alterations to a distinctive chromatin higher-order structure already possessing transcription factor binding sites in close proximity in three dimensional space.
Its pathogenesis is centered on autoimmune alterations with a distinctive cytokine profile.
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