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The EMS studies presented above demonstrate that while IHF binds to the minimal I1 duplex to yield a distinct (specific) retarded band, nonspecific binding interactions are also observed in a similar concentration range (compare panels A and B of Figure 3).
The results revealed GalNAc-T6 or GalNAc-T3-specific staining in clinical specimens (Figurse 2A and B) and a distinct specific band of GalNAc-T6 or GalNAc-T3 (data not shown) detected in the cytoplasmic fraction of pancreatic cancer cell lines, respectively.
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For TTF-1, only nuclear staining pattern was accepted as positive although our series contained a few tumours showing distinct specific cytoplasmic staining pattern without background.
DOI: http://dx.doi.org/10.7554/eLife.05996.002 A relatively small number of highly conserved cellular signaling pathways are responsible for a broad array of distinct, specific biological processes in metazoan development.
Among these expansions is a large nematode specific rGC clade comprising 21 genes in C. elegans alone; a vertebrate specific expansion in the natriuretic receptors GC-A and GC-B; a distinct vertebrate specific expansion in the guanylyl GC-C receptor and an echinoderm specific expansion in the sperm rGC genes.
A phylogenetic tree was constructed for ID1-like proteins in rice and Brachypodium which form a distinct grass specific clade of the C2H2 proteins (Figure 7C).
The fact that loss of Topo II only affects the Su(Hw) insulator subclass supports the conclusion of a distinct and specific role for this insulator.
We here demonstrate that this view is an oversimplification and that the subtelomeric regions of the S. cerevisiae genome have a distinct, chromosome specific organization, which is dependent on the precise location of X and Y' elements.
Collectively, our data indicated that Oct4 has a distinct and specific role in the maternal-embryonic transition, in controlling genes encoding post-transcriptional regulators, in addition to its conserved functions shared amongst pluripotent cell types.
However, whether DL-101+ cells represent a distinct subset specific to in vitro culture microenvironment remains to be further investigated.
Our light- and electron-microscopy immunohistochemical analyses revealed a distinct area specific distribution and an age-related increase of KCC2 protein.
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