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A sequence that uniquely characterizes a peptide provides a distinct site to generate novel agonists.
Like ADI-15946, the pan-ebolavirus mAb ADI-15878 also binds into a cryptic pocket at a distinct site in the GP base, that is typically occupied by the N-terminal tail of GP2 when not bound by the mAb21.
Importantly, NeoR6 alone does not affect cell migration, indicating that NeoR6 interacts with CXCR4 at a distinct site that is important for HIV-1 entry and mAb 12G5 binding, but not to CXCL12 binding or signaling sites.
The CD8 co-receptor also binds to pMHCI, but at a distinct site, and allows the potential for tripartite TCR/pMHCI/CD8 interactions, which can increase T cell antigen sensitivity.
It coordinates positioning at a distinct site and keeps contained cells close to the capsule.
JAM is a distinct site from the company's original social network for kids, DIY.org, which is also centered around learning and kids' creative or intellectual interests.
Similar(16)
This is another example of the absence of a distinct termination site and an incremental, non-site-specific termination.
These compounds form a crystal structure with one distinct site for barium and another for the lanthanide.
If K+ and Mg2+ act by binding to a distinct binding site at the surface or in a more buried location, this site would be additional to that which binds Na+ selectively.
In cells, obatoclax is strongly membrane associated but can be redirected to a distinct membrane site dependent upon the presence of excess, ectopic membrane-anchored Bcl-2 at that site [ 14].
The second step occurs in a distinct reactive site located on the other side of the molecule, and requires the diffusion of PGG2 to this site.
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