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Predominantly, East Asian CagA proteins do not have the WSS but, instead, possess a distinct sequence in the corresponding region, which is designated East Asian CagA-specific (ESS) [ 10].
Hypothetical models of Alzheimer's disease progression have been proposed (Aisen et al., 2010; Frisoni et al., 2010; Jack et al., 2010) that describe a distinct sequence in which different biomarkers become abnormal.
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This article was reviewed by Patrick Forterre, Eugene Koonin, and Gáspár Jékely Archaea were first discovered because of a distinct sequence signature in their ribosomal RNA [ 1].
Nevertheless, each miRNA possesses a distinct sequence difference in its seed region, the portion of the miRNA (nucleotides 2 to 8) that interacts with target mRNAs [ 15], implying the miRNAs serve non-overlapping functions that are further expected to depend upon target gene expression in specific cell types.
It is possible to map each symbol in G F(q = 2 p ) to a distinct sequence of p bits; in other terms, the binary representation of a is b p − 1 0 = ( b p − 1, b p − 2, …, b 1, b 0 ), where b i ∈G F(2).
They describe a distinct sequence of biomarker transitions in which CSF measures are the earliest to become abnormal, followed by atrophy rates, and finally cognitive test scores and regional brain volumes.
The FLT3 duplication predicted in A08823 has a distinct sequence from the FLT3 duplication predicted in A08878.
Human APC with UbcH10 appears to operate according to a different strategy, as it requires a distinct sequence motif, the TEK box, in both the substrate and ubiquitin for modification (Jin et al, 2008).
In amyloid-positive (cerebrospinal fluid amyloid-β1 42 < 192 pg/ml) or amyloid-β1 42 (one or more APOE4 alleles) subjects, the model predicts with high confidence that the cerebrospinal fluid biomarkers become abnormal in a distinct sequence: amyloid-β1–42, phosphorylated tau, total tau.
Indeed the 23,990 non-redundant Onthophagus sequences match a total of 14,223 distinct sequences in the NCBI NR protein database (Table 2).
We found a total of 7 distinct sequences in HvPG, two of which were not unique to this dataset, i.e. EZ407177 and EZ407232.
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